Bills' full 2021 regular-season schedule
Timothy T Ludwig / Getty Images Sport / Getty
The NFL announced its complete 2021 regular-season schedule Wednesday. See below for matchups, dates, and start times for the Buffalo Bills.
| Week | Opponent | Date | Time (ET) |
|---|---|---|---|
| 1 | vs. Steelers | Sept. 12 | 1 p.m. |
| 2 | at Dolphins | Sept. 19 | 1 p.m. |
| 3 | vs. Washington | Sept. 26 | 1 p.m. |
| 4 | vs. Texans | Oct. 3 | 1 p.m. |
| 5 | at Chiefs | Oct. 10 (SNF) | 8:20 p.m. |
| 6 | at Titans | Oct. 18 (MNF) | 8:15 p.m. |
| 7 | Bye | - | - |
| 8 | vs. Dolphins | Oct. 31 | 1 p.m. |
| 9 | at Jaguars | Nov. 7 | 1 p.m. |
| 10 | at Jets | Nov. 14 | 1 p.m. |
| 11 | vs. Colts | Nov. 21 | 1 p.m. |
| 12 | at Saints | Nov. 25 (Thanksgiving) | 8:20 p.m. |
| 13 | vs. Patriots | Dec. 6 (MNF) | 8:20 p.m. |
| 14 | at Buccaneers | Dec. 12 | 4:25 p.m. |
| 15 | vs. Panthers | Dec. 18 or 19 | TBD |
| 16 | at Patriots | Dec. 26 | 1 p.m. |
| 17 | vs. Falcons | Jan. 2 | 1 p.m. |
| 18 | vs. Jets | Jan. 9 | 1 p.m. |