Jan. 6, 2011: Despite being the consensus No. 1 overall pick, Luck shocks everybody by announcing he'll return to college for his redshirt junior season. In the end, the decision doesn't hurt his draft stock one bit.

March 7, 2012: After Peyton Manning missed the entire 2011 season due to neck surgery, the Colts unexpectedly release their iconic QB. It's a strong indication that the team plans to draft Luck with the No. 1 pick.

April 26, 2012: After announcing their intentions, GM Ryan Grigson and the Colts officially select Luck first overall, signaling a new era in Indianapolis. Three months later, Luck signs a four-year deal with Indy worth $22 million.

2012: Luck lives up to the hype in his rookie season, leading the Colts to an 11-5 record and setting a new mark for passing yards by a first-year QB (4,374). The team even makes the playoffs, but falls to the Ravens in the wild-card round.

Jan. 4, 2014: In one of his best performances, Luck tosses four TDs while turning a 28-point deficit into a 45-44 win over the Chiefs in the 2014 AFC wild-card round - his first playoff game at home.

2014: Luck is a different beast in his third season. He leads the league with 40 TD passes, throws for a career-best 4,761 yards, and takes the Colts all the way to the conference title game, where they fall to the eventual champion New England Patriots.

Sept. 27, 2015: Luck sprains his right shoulder in a 35-33 win over the Titans. It's the start of an injury saga that ultimately derails his career. Luck manages to finish that game, but then misses the next two contests due to his shoulder.

Nov. 8, 2015: Luck suffers a lacerated kidney and a torn abdominal muscle after taking a nasty hit from the Broncos in Week 7. The Colts announce he'll miss two-to-six weeks, but Luck doesn't play again in 2015.

Jan. 2017: Nearly two years after originally spraining his right shoulder, Luck undergoes surgery to fix the lingering issue. Colts owner Jim Irsay says Luck will be ready for the following season, but the QB misses the entire campaign.

2018: In his first year back, Luck tosses 39 TD passes and steers the Colts to an upset win over the Texans in the wild-card game before falling to the Chiefs. For his efforts, Luck earns the 2019 Comeback Player of the Year Award.

Aug. 24, 2019: At the age of 29, Luck confirms that he's retiring from the NFL, effective immediately. The four-time Pro Bowler cites constant injuries and rehab stints as his main reasons for stepping away from the game.