Rams' Henderson unlikely to play MNF vs. Cardinals due to COVID-19

The Los Angeles Rams placed running back Darrell Henderson on the COVID-19 reserve Saturday, the team announced.

Henderson is unlikely to face the Arizona Cardinals on Monday Night Football as a result. He needs to test negative twice on both Sunday and Monday before he's cleared to play.

Head coach Sean McVay said Saturday Henderson was feeling sick during practice and went for COVID-19 testing, according to Pro Football Talk's Josh Alper. Los Angeles placed him on reserve hours later.

Henderson, the Rams' leading rusher this season, already entered this week battling a thigh injury that sidelined him in last Sunday's victory over the Jacksonville Jaguars. He was active against Jacksonville but didn't play any snaps.

The 24-year-old tops L.A. with 648 yards (4.6 per carry) and five touchdowns on the ground this year. Henderson's also caught 27 passes for 172 yards and three scores.

The Rams expect Sony Michel to carry the load at running back if Henderson remains out. The former first-rounder racked up 121 rushing yards and one touchdown versus the Jaguars in Week 13.